Custom Plasmid
Manufacturing Services

PlasmidPros provides a custom service to manufacture your plasmid DNA by producing the plasmid DNA to your specifications. Together we’ll develop a statement of work agreement to produce the plasmid DNA to yield, purity and quality control.

Custom Plasmid Manufacturing Services

PlasmidPros provides a custom service to manufacture your plasmid DNA by producing the plasmid DNA to your specifications. Together we’ll develop a statement of work agreement to produce the plasmid DNA to yield, purity and quality control.

Key Benefits

  • Three levels of purity research, development and pre-clinical
  • Established QC procedure to choose from
  • Optimization of yields from low copy plasmid
  • Experience with AAV and Lentiviral vectors
  • Pricing levels are adjusted for your needs
Purity Grades
Plasmid DNA Manufacturing Services Scale Application Production
Research Grade 100ug-2.5mg In vitro R&D or preclinical studies R&D for cloning, vector construction, optimizations, protein expression and transfection
Development Grade 100ug-1g In vitro Research and Development studies Low Endo Toxins for sensitive cells
Pre-Clinical Grade >1g Toxicology, vector production optimization for clinical trials, and as template for mRNA production Dedicated Segregated Systems and Quality Control
Quality Control
QC Items Specification Method
A260/280 1.8-2.0 UV Absorption
Appearance Clear Visual Inspection
Concentration Per SOW UV Absorption
Supercoil content >80% Agarose Gel
Residue RNA Not Visible Agarose Gel
Genomic DNA Not Visible Agarose Gel
Restriction Digest Matches Reference Agarose Gel
Endotoxin Assay 0.1 EU/ug plasmid DNA LAL Assay
BioBurden Assay No Growth Agar plate for two days
ITR Integrity ITR cuts and is visible on Agarose Gel Enzymatic Digestion and Agarose Gel